Another COVID-19 Pill-” Paxlovid”

Pfizer announced its investigational novel COVID-19 oral antiviral medicine , Paxlovid reduced hospitalization & death. The adminstration has also arranged to purchase 20 million corses of drug. It will be manufactured & distributed to pharmacies in weeks & months.

It is orally bioavailable drug used against HIV that is active against M*pro, a viral drug that play an essential role in viral replication by leaving the 2 viral polyproteins . It has demonstrated antiviral activity against all coronavirus that are known to infect humans. It is ritonavir , a strong cytochrome P450 ( CYP) 3 A4 drug and boosting agent that has been used to boost HIV . How may tablet are needed? After it is prescribed, Paxlovid is administered as three tablets taken together orally twice daily for five days, for a total of 30 tablets. What are the side effects? Possible side effects of Paxlovid include impaired sense of taste, diarrhea, high blood pressure and muscle aches, says the FDA. Using Paxlovid at the same time as certain other drugs may result in “potentially significant drug interactions.” Consult with your doctor. Using Paxlovid in people with uncontrolled or undiagnosed HIV-1 infection may lead to HIV-1 drug resistance, the FDA said. How did Paxlovid performed in clinical studies? Paxlovid significantly reduced the number of hospitalization or death from COVID-19 by 88 percent, compared to placebo among patients treated within five days of symptom onset and who did not receive COVID-19 therapeutic monoclonal antibody treatment.

It is developed by Pfizer and can be taken at home to help keep high- risk patients from getting so sick that they need to be hospitalized.

According to Kaiser health information it not always easy to find a prescription; one individuals told that RPR that it took an usual amount of knowledge and connections.

The medication company named Pfizer is taken a stepping towards vaccine named “Paxlovid” to reduce hospitalization and may offer to India at lower prices.