COVID19 drug development is basically a research process to develop preventative therapeutic prescription drugs which may lower the severity of coronavirus disease 2019 (COVID19). Internationally, by November 2020, several hundred drug companies, biotechnology firms, university research groups, and health organizations are trying to develop over 500 potential therapies for COVID19 disease in various stages of preclinical or clinical research.
As with protein, the contents of other nutrients in foods determined by chemical or physical analysis may be quite misleading in terms of the nutrient status of a food. Apart from amount, what is important is whether the nutrient is in a form that can be utilized in metabolism; that is, whether the nutrient is bioavailable. For example, adding small iron pellets to cereals would increase their iron content, but the iron would not be very available to people eating the cereal and, therefore, be of little value.
A balanced diet will not be the same for everyone. We’re all different and often, individuals will require different amounts and types of nutrients. What you need will depend on age, gender, lifestyle, health and the rate at which your body works. Eating a balanced diet is key in maintaining good health and keeping your body in optimum condition. A balanced diet doesn’t cut out food groups; it consists of a wide variety of foods to support your body and keep you energised, motivated and healthy.
Age-related diseases are the leading cause of death worldwide, and they are also the leading source of concern for people concerned with global healthcare spending, both now and in the future. The CNS, vascular structures, joints, bones, the renal system, and other systems and tissues will be the focus of the special issue on age-related disease. The disorders must all be age-related, and the papers must seek to explain how the ageing process contributes to the pathology.
Organ and tissue loss through disease and injury motivate the development of therapies that can regenerate tissues and decrease reliance on transplantations. Regenerative medicine, an interdisciplinary field that applies engineering and life science principles to promote regeneration, can potentially restore diseased and injured tissues and whole organs. Since the inception of the field several decades ago, a number of regenerative medicine therapies, including those designed for wound healing and orthopedic applications, have received Food and Drug Administration (FDA) approval and are now commercially available.
The composition of waste is greatly influenced by disposable plastic-based personal protective equipment (PPE) and single-use plastics by online shopping for most basic necessities. The use of PPEs and single-use plastics during the pandemic not only increased the quantity of medical waste but also altered the average density of the medical waste. Waste generation amid COVID-19, especially discarded PPEs and single-use plastics, has been an environmental and public health crisis around the world, particularly in countries with developing economies and those in transition. Safe solid waste management is already a matter of major concern in these countries where safe and sustainable practice is scarce and healthcare waste has not been adequately regulated. India is generating tonnes of hospital waste in just a few months, in which Maharastra is the highest contributor because it has the highest number of COVID-19 cases and hence the waste produced.
Black Bags: These are to be used for non-bio-medical waste. In a hospital setup, this includes stationary, vegetable and fruit peels, leftovers, packaging including that from medicines, disposable caps, disposable masks, disposable shoe-covers, disposable tea cups, cartons, sweeping dust, kitchen waste etc.
The Bio-medical Waste (Management and Handling) Rules, 1998 and additional amendments were passed for the regulation of bio-medical waste management. Every state’s Pollution panel or Pollution management Committee are chargeable for implementing the new legislation. New laws have an effect on the distribution of medical waste by medical professionals into their correct recepticals.
Biomedical waste should be safely and efficiently identified, segregated, stored, transported and disposed after appropriate treatment. Its effective implementation in our community is of prime importance to protect public health and environment. With a growing population, biomedical waste is also growing in quantity in our country. Management of this waste is a rising concern in India. Segregation of Bio-Medical Waste at its origin is the key to the efficiency of waste management. Following regulations and scientifically managing Bio- Medical Waste is in the best interest of the public as well as the environment. It is really important to completely destroy the waste and it should be destroyed by following the norms so that it cannot transmit infection to anyone or harm anyone especially in present situation.
Medical care and hospitals are basic need for good life, well-being and health. But with this they generate a lot of waste which can be hazardous, toxic and lethal for humans and other living beings because it can be a main reason for transmission of diseases. Since beginning, the hospitals are known for the treatment of sick persons but we are unaware about the adverse effects of the garbage and filth generated by them on human body and environment. Now it is a well established fact that hospital waste is a potential health hazard to the health care workers, public and flora and fauna of the area.
Bone development involves the aggregation of mesenchymal stem cells into mesenchymal condensations, which is partly similar to tooth development but without the epithelial invagination. Bone has a high potential for endogenous self-repair.There are two types bone formation: intra-membranous and endochondral. In endochondral bone formation, the mesenchymal condensations first undergo chondrogenesis and then ossification to form cartilage and bone. During adulthood, bone possesses the intrinsic capacity for regeneration throughout life. In most bone injuries or fractures, the damaged bone tissue can be functionally regenerated by the local cells.
There is a long history of investigations into pancreatic regeneration, going back nearly a century. The epidemic of diabetes in recent decades has spurred numerous studies on pancreas development, homeostasis, and regeneration. Animal studies have suggested that the exocrine pancreas possesses an intrinsic capacity for regeneration and thus can make a rapid and full recovery from exocrine diseases such as acute pancreatitis. By contrast, the endocrine islets have limited regenerative capacity in adults.
Xenotransplantation is the transplantation of cells, tissue or other organs between phylogenetically different species. The process of grafting organs or tissues between members of different of different species. It is any procedure that involves the transplantation, implantation or infusion into a human recipient of either live cells, tissues or organs from a non human animal source or human body fluids, cells, tissues, or organs that have had ex-vivo contact with live non human animal cells, tissues or organs. The development of xenotransplantation is driven by the fact that the demand for human organs for clinical transplantation far exceeds the supply.
Prophase which is the first stage of karyokinesis of mitosis follows the S and G2 phases of interphase. Prophase is marked by the initiation of condensation of chromosomal material. The chromosomal material becomes untangled during the process of chromatin condensation.
Cell division is very important process in all living organisms. The cell cycle is a process a cell will go through to replicate all of its material and divide itself from one cell into two identical cells. During the division of a cell, DNA replication and cell growth also take place. All these processes, i.e., cell division, DNA replication, and cell growth have to take place in a coordinated way to ensure correct division and formation of progeny cells containing intact genomes. The sequence of events by which a cell duplicates its genome, synthesises the other constituents of the cell and eventually divides into two daughter cells is termed cell cycle.
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