Dexamethasone- Corona Vaccine Update!!!

Finally some good news today dexamethasone is now being called a major breakthrough based on a recent randomized controlled trial in the UK. Dexamethasone also known as Decadron is an example of a glucocorticoid are sometimes referred to as corticosteroids other examples of glucocorticoids include hydrocortisone methyl prednisolone prednisolone, prednisone beta methazone and triamcinolone so glucocorticoids are a class of steroid hormones that bind to the glucocorticoid receptor in the body cortisol aka hydrocortisone is the glucocorticoid.

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We naturally make in our body it’s essential for life it regulates or supports various cardiovascular metabolic and homeostatic functions it also plays a big role in our immune system especially when it comes to reducing certain aspects of inflammation this is why we use them all the time in medicine we sometimes give these steroids for asthma copd rheumatologic type diseases and countless more diseases. Sometimes it is also given for steroids for meningitis and also for some forms of cancer we also give them in the early course of severe ards acute respiratory distress syndrome whether that ards is due to infection such as pneumonia or vaping lung injury or whatever the cause for severe ards we typically give methylprednisolone or solumedral at a dose of one milligram per kilogram per day. So, for most people that ends up being around 80 milligrams per day so this is the equivalent of 15 milligrams of dexamethasone the idea here is to suppress the cytokine storm that has taken place meaning that the massive amount of inflammation that causes lung damage and can indirectly cause damage to other organs as well our body naturally makes cortisol in our adrenal glands specifically in the zona fasciculata of the adrenal cortex the adrenal gland then secretes cortisol into the bloodstream and the cortisol travels to different tissues of the body and then binds to the glucocorticoid receptor inside cells it then stimulates the cell to make more anti-inflammatory proteins and causes the cell to make less pro-inflammatory proteins but giving someone glucocorticoids meaning steroids to someone who has an infection is somewhat of a tricky thing because the fear is that if you suppress the body’s immune system it has the potential to make the infection worse. Sometimes the body’s immune system does more damage than the actual infection for example in cases of meningitis that is due to either streptococcus or tuberculosis we give steroids because the medical evidence shows that they have better outcomes when we do so and giving someone steroids for viral pneumonias like influenza is more controversial because doing so generally leads to worse infection with that said if the viral pneumonia is so bad to the point of causing severe ards most doctors will give steroids in that situation. So this is why, the general medical guidelines so far recommend against giving steroids for covert pneumonia unless the patient has severe ards and we’ve been waiting for randomized controlled trials to come out for steroids in covid and here we are now with this study so in march of 2020 the recovery trial which stands for randomized evaluation of covid-19 therapy was one of the randomized control trials that actually looked at several different potential treatments for covid which included low-dose dexamethasone this trial was done in the UK.

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Image source: Sky News

Over 11 500 patients in it so this trial has not been peer reviewed as of has not been published in the journal yet so everything I know so far is based on what’s been released to the general public in this trial over 2100 patients were randomized to receive dexamethasone specifically six milligrams once per day for 10 days and this group was compared with over 4 300 patients that were randomized to the standard care alone so 6 milligrams of dexamethasone is the equivalent of 32 milligrams of methylprednisolone so this is about half the dose we would typically use for someone with severe ards so among the patients who received standard care alone 20-day mortality was highest in those who required mechanical ventilation this was 41 and then intermediate in those patients who required supplemental oxygen only this was mortality rate of 25 percent and the mortality rate was lowest among those who did not require supplemental oxygen in which that mortality rate was 13 for patients who were on mechanical ventilators dexamethasone reduced mortality from 41 percent to 28 percent for patients who needed supplemental oxygen it reduced mortality from 25 percent to 20 percent and there was no benefit among those patients who do not require supplement oxygen in other words if someone only had mild disease there was no point in giving dexamethasone so based on these results one death would be prevented by the treatment of around eight ventilated patients. So that’s the number needed to treat for ventilated patients and then the number needed to treat for the ones who required supplemental oxygen that number needed to treat would be 25 so these preliminary results are significant but it doesn’t mean that dexamethasone is a miracle drug it’s certainly not a cure but it does seem to help based on these numbers index and methazone could be of huge benefit and not just rich countries but poorer countries as well because this drug is very cheap and is widely available so this is great news and very exciting but there are still a lot of questions that need to be answered like what is the ideal dose should we use higher doses in patients who are mechanically ventilated with ards and when will it be approved for use in the united states and we’ll get these answers pretty soon now another.

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Interesting question is should we give decadron dexamethasone to people who have mild disease now even though this study didn’t show any benefit the reason why i bring this up is because some people start out with mild disease and then go on to have moderate or severe disease and we have no way of predicting who goes on to do that and also it happens very quickly lots of times someone could be doing just fine and then all of a sudden within hours they all of a sudden are deteriorating and they have severe disease so should we give those patients decadron regardless is there any harm doing so that’s another question that remains to be seen.

A Story of African Diamonds…

It’s a far cry from the clean, mechanized mines of South Africa, but it’s how much of Africa’s gemstones are mined: men dig by hand in pits, gravel and stream beds, looking for telltale signs of that elusive stone that will make them rich – or at least bring in enough money to sustain them and maybe secure the family’s future. Over one million diggers search for diamonds this way in Africa. They make less than a dollar a day,  while the global diamond trade nets an estimated $80 billion a year. But, economic woes are not the only human toll of the gem industry.

In countries like Angola, the Democratic Republic of Congo, and Sierra Leone, diamonds were used by armed militias and rebels to fan civil war and inflict misery on the population. These became known as “blood diamonds.” Global Witness was one of the first non-governmental organizations to focus on the issue. Speaking with VOA in London, Annie Dunnebacke says the group set out to document the tragedy of conflict diamonds. “Sierra Leone is one of the most notorious cases where hundreds of thousands of people died as a result of the conflict that saw the eastern part of the country, where the diamond fields are, controlled by the Revolutionary United Front, a rebel group backed by then Liberian president Charles Taylor,” says Dunnebacke. “Horrific destruction and havoc were wreaked, especially upon the civilian population really, because the diamonds represented an economic incentive for the war to continue.”

The horrors of that war shocked the public, especially the scenes of innocent men, women, and children with their limbs cut off by rebels, and youngsters being forced into combat. Efforts to publicize the link between the atrocities, the warlords, and the diamonds paid off.

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The movie Blood Diamonds helped. In it, Leonardo DiCaprio plays an ex-mercenary who sells arms to Sierra Leone rebels in exchange for diamonds. In the end, though, he gives up the business and helps publicize the illicit trade. Global Witness was an advisor on the film, and Annie Dunnebacke says it had an impact. “I think bringing the message is sort of Hollywood terms to a much wider audience than possibly our reports get to, it does have value,” she says.

Eventually, international pressure made the diamond industry sit up and listen. In 2003, the Kimberley Process came into being. It requires member governments to certify that exports and imports are free from blood diamonds. Industry associations said they would comply. Tom Tweedy is a spokesman for DeBeers, the world’s largest producer of. He says the Kimberley Process is a good way forward. “We have a system, and however imperfect it may be, it is probably the only comprehensive system of its type in the world,” says Tweedy.

At the World Diamond Center in Antwerp, Director Philip Claes says that before the Kimberley Process, conflict diamonds accounted for 4 to 15 percent of rough diamonds traded worldwide. “Today, conflict diamonds account for only 0.2 percent of all rough diamonds traded worldwide,” says Claes.The emphasis is on certifying the origin of the diamonds to weed out goods traded illegally. Annie Dunnebacke of Global Witness says it’s a good start but there are loopholes.

“There are huge weaknesses ranging obviously from porous borders in African artisanal producing countries and basic lack of infrastructure, corruption, things like this which are stopping the scheme from being implemented effectively, things that encourage a lot of smuggling, cross-border smuggling,” she says. In Johannesburg, diamond trader Janine Chaveau agrees. “I know quite a few people who are multi-millionaires who have never dealt in legal diamonds,” she says, “it’s always been illegal, blood diamonds.”

Chaveau says she has been offered many undocumented diamonds. She says if they don’t have papers, she doesn’t touch them. But, it’s not just diamonds that are causing trouble. More than 90 percent of the world’s rubies come from Burma, a poor country with a military government that controls the sale of gems. The trade helps maintain the government in power. Human rights activists are working to tighten sanctions against Burmese rubies. But, like with diamonds, the potential profits are large and many are willing to look the other way.

Rights activists are hoping consumers will start to ask more questions of the jewelers to make sure that the gemstone they buy is not sullied by anguish and blood.

One more attack = Indo-China WAR!!!

The relation between Indian and Chinese army are now being worse. India holds a record of never attacking any of the army first till date. Many near by countries think that India is weak and cannot attack first, but this is our spirituality and religion to avoid any fight, but when the things get worse there need to be done something. India never approach any army for fight it always keep the things calm and to solve the problem with words and not the wars. India always gave a extraordinary action in case of any mischief done by the opponents, India carried out many operations like:

  • Operation Vijay
  • Operation Meghdut
  • Operation Surya Hope
  • Operation Brasstackes
  • Operation Cactus and many more to list…

India also gave a very strong answer of the Pulwama attack. India has the strongest army and technology support from Russia and US.

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Recantly, India was betrayed by dragons during a normal peace talk Chinese army betrayed Indian army by sudden attack on our prestigious soldiers. In this betrayal our 20 soldiers lost theirs lives for India:

 

  1.  Col B Santosh Babu
  2.  Nb Sub Nuduram Soren
  3.  Nb Sub Mandeep Singjh
  4.  Nb Sub Satnam Singh
  5.  Hav K Palani
  6.  Hav Sunil Kuma
  7.  Hav Bipul Roy
  8.  Nk Deepak Kumar
  9.  Sep Rajesh Orang
  10.  Sep Kundan Kumar Ojha
  11.  Sep Ganesh Ram
  12.  Sep Chandrakanta Pradhan
  13.  Sep Ankush
  14.  Sep Gurbinder
  15.  Sep Gurtej Singh
  16.  Sep Chandan Kumar
  17.  Sep Kundan Kumar
  18.  Sep Aman Kumar
  19.  Sep Jai Kishore Singh
  20.  Sep Ganesh Hansda

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Image source: BBCnews

In return Indian army gave an dangerous answer with their 35 troops by killing. PM Modi gave freedom, if in near future again this type of activities are done by Dragons than Indian army can do anything without any upper orders. Indian army are ready with thier backpacks and loaded arms and waiting for activities by dragons and it will be close to WAR.

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Image source: Navbharatimes.com

World Picnic Day…

We celebrate world picnic day on 18 June, and It’s often claimed that life is no picnic but today it is! International Picnic Day is a chance to eat out in the open air with friends or family. The word “picnic” comes from the French language, and it’s believed this type of informal outdoor meal became a popular pastime in France after the Revolution. As fans of Jane Austen’s novels will know, 19th-century picnics were elaborate social occasions, with menus featuring a wide range of cold meats and pies that took days to prepare. International Picnic Day is celebrated in many countries, though its origins are uncertain. Charity events, school picnics, and all kinds of other group meals are organized to mark the occasion. You could also bike, walk or hike to a nearby beauty spot, or just take your sandwiches and cold hard-boiled eggs into the garden and enjoy an al fresco lunch.

International Picnic Day is observed on June 18, every year. It is a day to encourage people to go outdoors and enjoy a hearty meal in nature, with other people’s company. In the early days, people used to go on a picnic as an escape from their daily lives. The true origin of International Picnic day remains unknown, but it can be traced back to the end of the French Revolution and the Victorian Era. This day is also marked by various charity events and school picnics. People all around the world meet their friends and family and go on picnics. They generally used to carry food, outdoor games, soft drinks, juices, and other essentials to share it with their travel partners. According to the Guinness Book of World records, the largest Picnic took place in  Portugal. In Australia’s Northern Territory, the International picnic day is celebrated in August on the first Monday of each year. It is a popular concept in that area and the general public gets a day off on this day. Schools and Colleges are also shut on this day.

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Asian people do not give any importance to the picnic day, and this day always celebrated in Australia and the U.S., Australian celebrate Picnic Day events since the late 1800s in Northern Territory. The Harts Range Races in Central Australia are held each Picnic Day long weekend. The races began in 1946 when three brothers Bennett, Quinton, and Kil Webb from Mount Riddock Station raced stockman Jack Schaber and the regional policeman Senior Constable Bob Darken over a distance of about a mile to the Ulgarna Yards to determine who had the fastest horse.

Moreover, in the U.S., Picnic Day is organized by a board of directors consisting of 18–20 students, ranging from different backgrounds and talents. Directors are full-time students and active participants of other extra-curricular activities and events at UC Davis. Every year, the board of directors selects a theme that will reflect the mission and vision of that year’s Picnic Day, and they also organized a different kind of themes and parade marshals each and every year since 1942 the themes started and in 1962 the parade marshal was started.

Here are some advantages and benefits of a picnic:

  1. Spending time outdoors, basking in nature, breathing fresh air, and enjoying a great view. The pure air invigorates you and leaves you feeling rejuvenated.
  2. Spending time with family is always a great bonding experience. In the fast-paced, urbane lifestyle of today, there is often limited time for maintaining relationships with some of the most important people in your life.
  3. Since picnics often take place in warm environments, the tendency to participate in relaxing small talk is high.
  4. While picnics offer many social benefits, you don’t have to spend the entire time chatting up a storm.
  5. Meals prepared and eaten at home are usually more nutritious and healthy than eating out and particularly so when you bring food for a picnic.
  6. Eating lunch outdoors is a natural mood booster. You can be amazed at how much the lack of sun in your body can affect your mood.
  7. Picnics are a great stress buster as it helps reduce the stress and anxiety related to work and home.

Please, spend time with family at outdoor and spread awareness regarding it.

thanks for reading.

 

“An animal’s eyes have the power to speak a great language.”

It has been a long time since there is a debate, whether animals have been exploited for humans’ needs. However, More than 200 million animals are killed for food around the world every day – just on land. Including wild-caught and farmed fishes, we get a total closer to 3 billion animals killed daily. That comes out to 72 billion land animals and over 1.2 trillion aquatic animals killed for food around the world every year. In the United States alone, around 9 billion chickens hatch every year for the sole purpose of growing to an edible size and dying for human consumption. Animal suffering is the most direct consequence of consuming meat, but there are unintended consequences of eating animals, too.

All-around the globe, animals are used in a different way by humans to fulfill their need, they use it as food, making shoes, jewelry, irrigation, medical research, end experiments. Is it justified to use animals to human’s personals needs? not all animals grass-eaters, they also have to kill or hunt to fill their stomach, Video from the first large-scale investigation of intensive fish farming in Europe shows fish thoughtlessly scooped out of nets and thrown into plastic containers, where they slowly asphyxiated, Some of them miss the bin and flap to death on the floor. This video was disturbing, Some fish survive out of water for hours on their way to the slaughterhouse. If they’re still breathing when they get there, they die by a blow to the head. Nearly 300 wild sea animals are killed every year to feed one American, but that doesn’t include the fishing industry’s bycatch.

Considering the number of Americans that claim they only eat humane meat, it’s worth a quick math lesson. If 99% of farm animals in the U.S. are raised on factory farms, compared to about 90% globally, and 75% of Americans think they consume humane meat, the survey says that most of them don’t. Animals raised for food die by the millions in slaughterhouses around the world, and they do not think before eat. but the main thing is that animals also take revenge by spreading life threating viruses like swine flu and plague, even though human-made vaccines of these viruses, it had taken lots of human life.

If I talk about India, each and every day many animals have been killed by humans, even though the majority of the population is Hindu, and the coastal area also famous for fishing and fish farming, many famous franchises like K.F.C, Mc.donald, Subway, and Burger King provide chickens, beef, meats, poke, and many other animals eatable product. furthermore, in the fashion industry like L.V., Gucci, Prada, Zaara, and more,  provide clothes and fashion accessories like a leather purse, belts, leather shoes, and jackets that are obtained from animal’s flesh.

On the other hand, if we talk about science and research, in that process animals always be preyed by the scientist, and in recent news, they narrated that “Tests of other fast-tracked vaccines show that they have prevented infections in the lungs of monkeys.” they are so mean to not test on human or own self, they also not have an idea that there are lots of difference between the skin and immune system. there are many alternatives to reduce the suffering causes of animals.

Additionally, in India, there are many N.G.O.s, which always stands for animals rights, People for Animals India does a great job by saving street dogs in COVID-19 situation by serving food, shelter, and medicines. however, not only N.G.O.s but all people around the world stand for mutated animals, and if you wont to do great help, join the nearby N.G.O.s and save animals.

Be the follow “live and let live”

 

 

How to open a Franchise without money- US…

let’s talk about to open a franchise with no money so the first thing you can do, if you want to open a franchise with no money down is go to your friends and family look. I understand that that’s something that you may not want to do sometimes that’s a toughest conversation asking friends and family for money but I would assume if you’re willing to open a franchise and you have some skill sets you have a certain level of intelligence and a certain level of ambition so assuming that you have a good reputation and a good rapport with your friends and family then that’s the first place that you can go to get money to fund your franchise.

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Now when you’re approaching them for the money it’s important to be tactical and strategic about it and you don’t just say hey! can I borrow ten thousand dollars can I borrow twenty thousand dollars can I have fifty thousand dollars you have to go into it strategically so go into it with a business plan this is the franchise that I want to buy this is the amount of money that I need to get started this is a lot the amount of money that I think I will make with the franchise this is the time period which I can pay the money back to you and get on that loan repayment plan, another way to approach getting money from feds and friends and family to fund your franchise is to ask them to be a partner with you so although they may not want to work in the franchise themselves maybe they’re more willing to give you money or lend you money for the franchise if they are an owner or an investor with you so maybe you’re the one that runs the franchise and you handle the day-to-day operations the sales managing the staff managing the overall business and they get a percentage of the profits as a way of paying them back.

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The next way that you can fund a franchise is to get a loan and before you read about that real quick with the franchise so now in getting a loan to open a franchise business it’s important to note that one you’re going to need to have good credit and two you’re going to need to have an income that can support paying back. The loan and three the likelihood is you are still going to need money for the down payment on that loan if you get us an SBA loan which is Small Business Administration they require a minimum of 10% down from you in order to fund that business so what does that mean if you need $100,000 for your franchise business then that means you need to come up with $10,000 in order to here that loan so the question is how will you come up with that $10,000 and there’s a number of options that we’ll go over in a second of how you can do that one way you can do that is what we already talked about which is getting money from friends or family it’s so even with the Small Business Administration having a ten percent minimum requirement that you have to put towards the loan in order to open a business.

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Most lenders that issue SBA loans are going to require anywhere from 20% to 30% in order for you to secure that loan so again in that example if you’re looking to open up a business that’s a total of $100,000 you’re going to have to figure out a way to come up with twenty to thirty thousand dollars in order to secure that loan and so in a second I’m going to tell you about a strategy of exactly how you can do that without having to ask your friends or family for money another way that you can fund a franchise without having any money so to say is seeing if you have any 401k or retirement plans now as someone who has managed over a hundred million dollars over the course of career as a financial advisor typically. I would not recommend for someone to take money out of their 401k and that’s not what I’m recommending to you. So, I want to make sure that you get that clear because there are severe penalties and tax consequences that you should consult the tax advisor about but there are ways that you can leverage your 401k so if you’re still working with your employer you can take out a loan against your 401k in order to fund a business and when you take out a loan there’s one thing that you have to be very careful about the thing that you have to be careful about is that if you leave that employer and you have an outstanding loan they are going to make you repay that loan within a certain period of time usually it’s 60 days if that is the case if you don’t come up with the money and repay the loan for the 401k they count it as an early distribution you’re going to have to pay taxes on that money depending upon if it’s a pre-tax 401k and you may have to pay some penalties. 2 guys opened up first location they were going to need 300 just over $300,000 in order to get first location open so they had a significant equity in their home at that time and want to went ahead and apply for a home equity loan they secured a three hundred and ten thousand dollar home equity loan use that home equity loan to fund the business and to pay for the business about a year or so later they actually wind up moving they sold their house the home equity loan was paid for paid off and now they own the franchise in the business completely outright don’t have any loans on the business and then the last way that you can potentially buy or open a franchise with absolutely no money is to talk to the franchiser again it’s not about the resources it’s about your resourcefulness so it never hurts to ask them and to make a pitch if you’re truly excited and confident about the opportunity.

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Strength comes from struggle and rebel……

Everyone is aware of the word of rebels, and ones in while many of you are also done in your life at school, colleges, or other public places for gatting rights according to your demands. However, in the past also people have done rebels to get political rights, Sardar Vallabh Bhai Patel, Mahatma Gandhi, Subhash Chandra Bose,  Shahid Bhagat Singh, and more freedom fighter also have contributed for getting freedom from the British people. furthermore, a rebel is not the only way to get rights, instead, there is some legal process to do, which is made by the government of all counties.

The famous rebel incident happened between Indian solders and Kashmir’s citizens, this whole incident started from Kashmiri people, they started the attack by throwing stones on Indian soldiers and we all know that soldiers do not have rights to file at the time of the attack they have to wait for the order from the government, and then they can fire when the government gave the order to fire before that two or three soldiers had serious injuries, but when Indian army get the order then they did a great job by killing The 12-hour gunbattle ended with the killing of Junaid Ashraf Sehrai, a commander of Kashmir’s largest rebel group, Hizbul Mujahideen, and his aide. Junaid, son of senior separatist leader Mohammed Ashraf Sehrai, joined the rebel ranks in early 2018 after graduating in business management from the region’s main university.

However, in Bollywood, many people have done rebel against the nepotism but there some strong pillars, who don’t wont to do changes in the industry, they do not give chance to new people, many people wont to join the Bollywood and they give interviews and show their work buy doing the theater and making small and short films, but the big director and producer always support the famous personalities child-like Varun Dhawan, Ananya Pandey, and many more. But people like from small families and not wall background never chance to show them in front of society and what they can do for the community. celebrities like Pankaj Tripathi, Nawazuddin Siddiqui, Manoj Bajpai, Johny lever and Sushant Singh Rajput had done exceptional debut in Bollywood by doing small T.V. serials and theater, and look at how they become famous worldwide famous stars without showing their body or fighting skill, which is very common in nowadays movies, but this senior actor always wins our heart by delivering dialogues. people who do not have celebrity background they always have to struggle, and nowadays young personalities share messages they “they have struggled after sign 10 to 20 films and advertisement.” shame on them by spreading fake, abominable and detrimental rumors, we have proof, they said by their own word on a national television show like coffee with Karan, at the beginning of the carrier people say that I admire that person and i follow them, but after getting success they forget, by ignoring and do not talk about them.

if anyone wont to look perfect nepotism then look the last few film awards, where Ananya Panday aka miss.struggle received Zee cine Award for Best Debut Actress, Filmfare Awards for Best Debut Actress, and lately best fresh Talent of the year, moreover on another side Sushant Singh Rajput did not get any award even though, he has done grate lead role in chhichhore.

So, please guys don’t support fake people, instead of support upcoming and real struggle persons, who can motivate us by simply narrating their story, be a lone wolf do not depend on someone to make a clear way.

 

What to do at the time of depression!!!

If you’re depressed to feel a little bit better and I want to make sure you understand what those are but first I want to start by helping you understand what the typical signs and symptoms are:

1- One of the most common signs of depression is a feeling of sadness or irritability that is really pervasive and doesn’t seem to go away no matter what you do if you’re with friends if you’re by yourself the sadness just sort of becomes your reality irritability can also be present and this is much more typical in teens that they will present with more irritability than sadness when they’re dealing with depression.

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2- Feeling really hopeless and this can be hopeless about getting better it can be a sense of hopelessness about the future and the ability of sort of achieving your hopes and dreams and again it’s a very tough symptom to deal with because other people can tell you, know you have so much to look forward to or this great thing is happening in your life but if you’re really struggling with depression that hopeless this just kind of takes over and keeps you stuck.

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3- You should be aware of is something called anhedonia. This is really a fancy way of saying a loss of interest in things that you previously used to enjoy so for example you might really be into gardening and all of the sudden you find that no matter how many times you garden or if you try to garden there’s just not the same joy that you’re getting out of it that you used to or maybe you used to really be really social and enjoy spending time with your friends and you find that you just can’t bring yourself to get out of the house and to go and interact with these friends and it’s really difficult to deal with because it’s very hard to motivate yourself. When the things that really used to be what got you out of bed and got you ready for the day no longer hold the same enjoyment and pleasure.

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4- Either decreased concentration and/or indecision the difficulty with making decisions and this can be really difficult when you have to function either in the workplace or you have a lot of responsibilities at home because you’ll find that it’s harder to complete the tasks that you need to complete and if you do need to make decisions there’s almost like this decision paralysis where you find that you just can’t get yourself to the place of making choices.

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5- You should be aware of our changes in sleep and this can be either that you find yourself sleeping a lot more than you used to and having like a really hard time getting out of bed maybe you’ve never been a Napper and all of the sudden you’re taking a nap every day on the other side of the spectrum many people who are struggling with depression find that they can’t sleep that they’re racked with insomnia for the first time in their life and they’re laying in bed and their thoughts just keep running around and they’re feeling sad and they’re feeling hopeless and so either too much or too little sleep is a really cardinal sign of depression that you should be aware.

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6- You should be aware of our changes in appetite or weight and this can be either in the positive or the negative depression sometimes when people are depressed they find that they use food for comfort and end up eating a lot more than typical and gaining weight and sometimes when people are depressed they lose their appetite completely and don’t eat at all and find that they lose weight so if you’ve had any significant weight changes within the last couple months and you also have some of the other signs and symptoms we’re talking about it might be a good idea to consider that there’s some level of depression going on that you’re struggling with so another.

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7- Lastly sign of depression that we’re going to talk about today is a sense of worthlessness so and really this is very difficult for people to handle because it’s a sense that no matter what they do they’re not enough their life is not enough and it won’t ever be enough and this is such a difficult thing to be dealing with and so I think my overall message as you’re learning about these signs of depression is that if you’re experiencing these please reach out and make an appointment with a licensed professional to talk about this because this is something that can get better and you don’t need to struggle with it on your own if you think that you or someone you love might be struggling with depression please reach out and make an appointment with a licensed professional for an evaluation there are many therapeutic techniques that can help you or someone you love feel better and so I strongly encourage you not to hesitate to get the help that you need.

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Call on +91 730 459 9836 for a better help to Vandrevala Foundation if you are feeling depressed or you find someone else depressed. (https://www.vandrevalafoundation.com)

 

 

DEPRESSION…a serial killer !

Why do we wait for something big and devastating to happen that opens our up eyes for issues that are serious and should be taken care of ?

Recently with the famous actor Shushant Singh Rajput passing away, as he committed suicide shook the whole nation about how a person who was so happy, excelling in his career, what made him take such a step? Suddenly I see whole of the social media getting flooded with things on mental illness, depression , anxiety , importance of it and so on .….

This issue isn’t something new that has born recently. It has always been a serious issue which all of us in some way or the other have neglected. There are plenty of people out there who have, and who are still suffering from mental disorders severely and some acutely. Mental health is something we all need to take care of.

MENTAL ILLNESS AND DEPRESSION

Clinical depression has been linked to other mental illnesses, such as anxiety disorders, panic disorder, social phobia, and generalized anxiety disorder.

MY EPIPHANY…

Depression is debilitating.

Some people acknowledge it, some think it’s an attention call. For me, depression is like that bundle of laundry that you don’t want to show in your Instagram pictures. I never want to show my heap of laundry to the world, I want my life to seem content and put together, as if I folded and put away all my laundry right out of the dryer.

Depression can be the hardest when others just don’t understand you. Never ask anybody how they can be so sad that they could contemplate suicide. Because honestly most of the people in that situition don’t know. How did they make it to this moment? What did they do to deserve this sorrow?

Nobody really knows how to explain depression to someone. It’s so different for everyone and comes in so many different forms. Some people explains their depression as a weight that holds them down. Others describe it as a shadow that looms in the back of their mind, always taunting and trying to tear them down and then sometimes, depression is described like they are sinking. It’s like dabbling in an ocean of poison and barely catching your breath before you’re dragged back under. I don’t think people understand that depression is persistent. Some days it doesn’t feel as burdensome, it doesn’t tug and pull as hard. And other days, it knocks you down before you can even get out of bed.

I am always fighting this constant battle with myself past many years .. Yes! Me I may smile and laugh and seem happy, but know that, somewhere, in the back of my mind I’m struggling. It makes me feel like a failure, no matter what my successes. I feel worthless and like I’m a burden on everyone around me. After entering my teenage years till now I’ve been aggressive, argumentative used to reacting quickly on situations without understanding them, used to getting upset on small little things and have been called dramatic. It has become one of my biggest triggers, because most of my life I haven’t had that fight to defend it.

I get sad without any reason so often that I’ve created safe spaces. Currently, my safe place is my bathroom floor. Probably about at least 1 time in a month you can find me locked in my bathroom on the floor, crying. The lock on that door is the only form of power I feel I have when I feel everything is parting away.
Many times I have found myself on that bathroom floor contemplating life and how to make it past that very moment, will I? I have to say how thankful I am that I haven’t followed through. Life is so hard. Sprinkle on some depression, heck, dump it on – and life is now even more hard. Sometimes the low gets so low that it seems to take over, overwhelming you in a way that you could not have imagined beforehand.

Dressed from Penny to Gucci it’s a misconception that smile is the finishing touch to most outfits.We all give off the impressions that we are happy but this can be a very inaccurate representation of what we are actually experiencing.
People always say you should talk to someone, tell someone,but how do you put words on something so hard to even understand yourself? How do u explain someone that u want to live your life in peace but also you don’t know how you can? How do u explain that this no longer feels like a choice, that it controls you not the other way around.

Of course we are encouraged to TALK more these days but some of us including me wont even know where to start. some of us will Feel like we don’t have anyone to talk to and others will simply be sick of talking. Sometimes we do so much talking and thinking about whats going in our heads that we get even more confused by our own thoughts. This often leads us to say ‘ENOUGH’ and once again putting back on the brave face and deluding smile. By this we fail to get to the roots of our suffering. I am guilty of smiling so many times when I am actually freaking out from inside.
Why is it so hard to accept our own sufferings ? Well its not facile to accept your suffering because of thoughts in your head and ultimately your ego believes that you shouldn’t be suffering. That makes suffering and challenges we experience in life so much more daunting, arduous and scary.

Depression doesn’t have a face. you never know who is the girl around you always happy and cheerful must be struggling from inside or the boy who shows himself so tough maybe he needs someone to listen to him or be there for him. Nobody really knows how much the other person is hurt. We could really be beside someone who’s world is falling apart and we wouldn’t even know.

THE BIGGEST MISCONCEPTION OF THOSE WHO ARE SUICIDAL

People who believe those are suicidal are selfish- that they only think about themselves and not their loved ones. This is wrong ….. often those who are suicidal truly believe their loved are better off without them because they are such a burden.

Ergo, its important to be kind and tell others how much they mean to you even on their bad days. Often, people tend to not give enough importance to the person who’s suffering from mental issues and rather than giving a smile or telling the person that ‘they understand’, ‘they’re listening’ and that ‘they are there for the person’ they slightly bob their head, as if they understood yet they don’t.

There are people who often say that we can talk to them and they are always there, but when the time comes and we actually need help , they tell us to help our selves or often come to the conclusion that ‘we are in the problem because of our own wrong doings’.This far more worsens the situation for the person going through it. We are nobody to judge which  problem is big or small because we all are different and feel different emotions.

I HOPE YOU CHECK UP ON PEOPLE OFTEN EVEN IF THEY HAVE A BRIGHT SMILE, BECAUSE OFTEN BEHIND THAT BRIGHT SMILE THEY MIGHT BE FIGHTING THEIR OWN HIDDEN BATTLES.

Whenever someone says you have hurt them, don’t shut them out. You don’t get to decide if u have hurt them or not. Don’t make them feel like a fool for expressing their feelings. Don’t always be self-righteous and think you can never make a mistake. If knowingly or unknowingly your actions hurt someone, avoid doing it. You can save someone just by being kind and being there for them.

WHAT TO SAY :

  • You are not alone in this
  • You are important to me
  • You have me! And prove them not just saying it for heck of saying
  • I am not going to leave in your tough times
  • Tell them you care for them and what worth they hold
  • Tell them you understand ( only if you really do)
  • Assure them they are not weak or defective
  • Emphasize that there’s hope

It’s possible that you can say all the “correct” things and your friend will still become upset with you. Each individual have their own unique thoughts and feelings, and being irritated and upset is the nature of depression. Sometimes people will take it out on those trying to help them because they are hurting and don’t know where to direct those bad feelings. Whoever is nearby becomes a convenient target. If this happens, try not to take it personally. Stay serene and continue to do what you can to love and support your friend in whatever way they will allow.

WHAT NOT TO SAY :

Avoid saying such phrases

  • Don’t think about it
  • Be positive
  • I know how you feel – never say this because nobody really knows how the other person feels or is going through
  • Count your blessings
  • Your mood is bringing everyone down around you
  • Just smile and let it go
  • Its all in your head
  • No one ever said life was fair

Many people with depression think they are just feeling sad, and that it will go away with time. For some people, it does just that. But for 15 million others, depression is a constant feeling that does not go away on its own. In fact, WHO found that depression is the second greatest reason for disability in the world. 

I know everyone out there may not have depression, but everyone definitely have something hard they’ve experienced, everyone have something to share and everyone have something to relate to. We are nobody to judge someone else’s problem no matter how big or small it is. Well small issues only take a bigger step and why wait for that oblivious stage to come,why not lend a hand in the initial stages.

Let’s be vocal about our hard times, it’s healing, not embarrassing.

WE SHOULDN’T IGNORE WHAT IS HAPPENING IN OUR HEAD BECAUSE  ITS WHERE ALL OUR HOPES AND DREAMS LIVE.

Life after corona…

In amidst this global pandemic,life has become very harsh for many poor and middle class people. This lockdown has also locked the earnings making them struggle everyday to meet their daily needs. The biggest question of the hour has turned out to be”when will this pandemic meet an end?”.But it is necessary that we must focus on life after corona.

This corona virus has taught us many things ,it has helped in integration of people not only in the country but also worldwide. This virus has taught us that discrimination of people on basis of caste,religion,region has no sense. It has also became agent of mother earth wherein it brought the pollution levels significantly down all over the world. 

It is clear indication that we must start using non-conventional energy sources after this crisis. It is clear that we must understand that humanity is the only religion and serving needy is next to serving god. 

We should maintain social distancing at least for following year and help needy. If we all stand United and act wisely we will surely be victorious in this situation and once again we can live that golden days enjoying railway rides, shouting for our favourite team in stadiums and the birds chirping in the forest without our intervention, but for now we must stay home stay safe. 

It’s not stress that kills us, it is our reaction to it.

Stress name is enough to load stress on the human mind, however, every person in this world had passed through stress, but the beautiful thing is that how people can handle it and overcome from it, stress is a part of the human mind and Stress is a feeling of emotional or physical tension. It can come from any event or thought that makes you feel frustrated, angry, or nervous. Stress is your body’s reaction to a challenge or demand. In short bursts, stress can be positive, such as when it helps you avoid danger or meet a deadline, it totally depends on the human action on how we can handle positively or negatively by committing a crime or by suicide.

However, our whole life is full of stress, from birth to till death, like after having a birth people start taking decision regarding the future life, when we enter the school at the time teachers and faculty give homework and assignment to finish from home if we don’t complete it, have to face parents, so, we have this stress, further, 10th and 12th exam pass out stress, yet when we pass 12th anyhow, graduation and post-graduation stress, and latest job and marriage stress, at the end of the life stress of pain and diseases. But the major thing is that many people do not wait for old age they lost their life by suicide, their mind and heart are not enough strong to handle the load or not mentally prepare for further future.

In addition, our education system also have fault like they give dept education of History, science, maths, languages and many more, but they do not give lessons on how to handle depression, anxiety and stress, by organizing I.T. fair or science fair student only enjoy, it affects only a few hours. But organizing a stress relief program where students can understand how to handle any life turning modes. After completing the study, people try to find jobs or developing their business, but after a long struggle some get success or many get a failure, and that is the major turn of life if any person handles well, they get the real success in life.

Many famous celebrities are renown by their comeback from stress like famous cricketers Yuvraj Singh, and famous actor Akshay Kumar and Nawazuddin Siddiqui both belong to small and poor families but now every nook and corner people know them. However, in the year between 2009 to till date, around more than 100 celebrities commit suicide in that list include Stephanie Adams, Chester Bennington, David Berman, Joseph Brooks, David Buckel, Malik Bendjelloul and many more they all are from Hollywood, but recently a well-known actor Sushant Singh Rajput committed suicide it just bingeing of the journey and he did a great job by acting as lead actor in MS Dhoni the untold story, Kedarnath, Detective Byomkesh Bakshy!, and Chhichhore.

In Chhichhore, done a great job and he delivered a beautiful line “Hum haar jeet, success failure mein itna ulajh gaye hai … ki zindagi jeena bhool gaye hai … zindagi mein agar kuch sabse zyada important hai … toh woh hai khud zindagi” and by considering this line many failures get motivation and done grate thing in the life, but the lead actor committed suicide, which is not relevant, he has to share his problems with family or friends, he definitely gets a solution and he still present with us.

there are some exercise to overcome from it like, Yoga, Qigong, Walking, Gardening, Dancing, Circuit Training, play Tennis or do some boxing whit pillow on the wall, this all help to relieve stress. nowadays the best way to come out stress is by doing a party or hanging out with friends.

So, considering this all thing, give value to your life, and enjoy your life.

R.I.P. Sushant Singh Rajput

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Reason behind Sushant’s death- Terrible!!

On the late morning of 14th June 2020 an terrible incident took place which kept everyone in deli ma as the famous actor Sushant Singh Rajput and 34 years old guy from Patna commits suicide. What made a well settled actor made drive this step, reports says that Sushant Singh Rajput was in a sever depression from last few months and doesn’t talk much with the neighbors and watchman as well as relatives further the lockdown boost up this depression. The relation with Rhea Chakraborty were also at not good level this further made him in depression as last relation with Ankita Lokhande were also at red mark. Reports also show that he was living in a house which rented 4 lakhs per month and he was further in financial debt. He was living with one of his friend and 3 maids on 14 June after much trials of calling out to Sushant, amid finally decided to open the door, as the door opened it kept everyone shocked.

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Image source: Instagram (Sushant Singh Rajput)

A talented actor with name, fame, money, respect, young, potential was not excepted to leave the world this much soon. Yet there are many wish list he need to fulfill. Let us have some look.

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This is very unfair…

The movies in which Sushant performed:

  1. kai po che!
  2. Suddh desi romance
  3. PK
  4. Detective Byomkesh Bakshy
  5. M.S. Dhoni- The untold story
  6. Raabta
  7. Welcome to New York
  8. Kedarnath
  9. Sonchiriya
  10. Chhichhore
  11. Drive
  12. Dil bichara

It gives proof that depression, Stress, Anxiety doesn’t look at status.

If you need support or know someone who is under depression or suicidal, please reach out to mental health specialists or helplines. AASRA: 91-22-27546669 (24 hours) Sneha Foundation: 91-44-24640050 (24 hours) Vandrevala Foundation for Mental Health: 1860-2662-345 and 1800-2333-330 (24 hours).

 

Its time to roll up your sleeves and save a life – World Blood Donor Day 2020

Your little effort can give others second chance to live life.

Donating blood is one of the greatest ways to help humankind. By doing so, we save someone’s precious life, and that is a blessing in itself. 

On 14th June every year the world celebrates World blood donor day also known as WBDD  to raise awareness about safe blood donations and to thank those who voluntarily donate blood to save the lives of others.

This day is celebrated to mark the birthday anniversary of scientist Karl Landsteiner who won the  Nobel Prize for his discovery of the ABO blood group system. Before Carl detected blood groups, blood transfusions used to happen without knowing the various blood groups

2020 WBDD Theme

World blood donor day is marked as a global public health campaign by WHO. Every year there is a theme made for the day and this year’s World Blood Donor Day theme is ‘‘Safe blood saves lives’‘ with the tagline ”Give blood and make the world a healthier place”.

In the wake of coronavirus pandemic, the WHO will conduct a global virtual campaign this year with the objective to focus on the contribution an individual giver can make to improve health for others in the community.

Is it safe to donate while you are MENSTRUATING ?

It’s understandable where the idea comes from: your body is losing blood during menstruation already and you worry for your own health if you volunteer to give even more. But regular menstruation does not affect your ability to donate. You can safely donate blood during your period if it is required and your period will not be affected by the donation.

What to know before you donate blood:

  • The donor must be fit and healthy, and should not be suffering from transmittable diseases.
  • Age and weight- The donor must be 18–65 years old and should weigh a minimum of 50 kg.
  • Pulse rate- Between 50 and 100 without irregularities.
  • Hemoglobin level- A minimum of 12.5 g/dL.
  • Blood pressure- Diastolic: 50–100 mm Hg, Systolic: 100–180 mm Hg.
  • Body temperature- Should be normal, with an oral temperature not exceeding 37.5 °C.
  • The time period between successive blood donations should be more than 3 months

DONATE BLOOD AND MAKE A DIFFERENCE !

Donating blood is one of the most common ways people choose to give back to their societies . Despite the high demand and the general recognition of its importance, only about a fourth of the people who are able to donate blood do. Many people are not aware of just how important blood donations can be.  Approximately one of every seven people admitted to the hospital need blood. There are a lot of health benefits of donating blood :

  1. Giving blood can reveal potential health problems
  2. Giving blood can reduce harmful iron stores
  3. Giving blood can help your liver stay healthy
  4. Giving blood can help your mental state

The health benefits of donating blood are considerable—but of course, the most important part of the process is helping to save lives.

It’s time to roll your sleeves and save a life.Just 1 unit of your blood can save 3 lives. So why not take this day as an opportunity and make a difference in the society by acting responsibly.

You can share messages, why not blood?

The blood donation happens when a person voluntarily ready to transform their blood into communities without any charges, however, Donation may be of whole blood, or of specific components directly. Blood banks often participate in the collection process as well as the procedures that follow it.

The blood donation process discovered by English physician William Harvey in 1628 but after 36 years thy successfully done blood donation camp in England, the first blood transform done on a dog and Physician Richard Lower keeps dogs alive by transfusion of blood from other dogs people think it is funny incident but it is very seriously a successful transformation.

Today in the developed world, most blood donors are unpaid volunteers who donate blood for a community supply. In some countries, established supplies are limited and donors usually give blood, when family or friends need a transfusion. Many donors donate as an act of charity, but in countries that allow paid donation some people are paid, and in some cases there are incentives other than money such as paid time off from work. Donating is relatively safe, but some donors have to bruise where the needle is inserted or may feel faint. Potential donors are evaluated for anything that might make their blood unsafe to use. The screening includes testing for diseases that can be transmitted by a blood transfusion, including HIV and viral hepatitis. The donor must also answer questions about medical history and take a short physical examination to make sure the donation is not hazardous to his or her health. How often a donor can donate varies from days to months based on what component they donate and the laws of the country where the donation takes place. Ex. in many countries the doner have to wait for two to three weeks to rebuild their blood counts and proper growth of their blood portion. A typical donation is 450 milliliters of whole blood, though 500-milliliter donations are also common. Historically, blood donors in India would donate only 250 or 350 milliliters.

There are two main methods of obtaining blood from a donor. The most frequent is to simply take the blood from a vein as whole blood. This blood is typically separated into parts, usually red blood cells and plasma since most recipients need only a specific component for transfusions. The other method is to draw blood from the donor, separate it using a centrifuge or a filter, store the desired part, and return the rest to the donor. This process is called apheresis, and it is often done with a machine specifically designed for this purpose.

What precautions have to take donor after blood donation, they have to lay down for 10 to 15 minutes at the bead, then take light refreshments, such as orange juice and cookies, or a lunch allowance to recover speedy, The needle site wound is covered with a bandage and the donor is directed to keep the bandage on for several hours. And in last avoid strenuous exercise and games, alcohol and other kinds of physical exercise.

People from non-science backgrounds have questions that how doctors store blood for a long time?, here is the answer, Red blood cells, the most frequently used component, have a shelf life of 35–42 days at refrigerated temperatures. For long-term storage applications, this can be extended by freezing the blood with a mixture of glycerol, but this process is expensive and requires an extremely cold freezer for storage. Plasma can be stored frozen for an extended period of time and is typically given an expiration date of one year and maintaining supply is less of a problem.

Here is the table display that, which blood group person can donate to whom.

If your blood type is: You can give to: You can receive from:
O Positive O+, A+, B+, AB+ O+, O-
A Positive A+, AB+ A+, A-, O+, O-
B Positive B+, AB+ B+, B-, O+, O-
AB Positive AB+ Only All blood types
O Negative All blood types O- only
A Negative A-, A+, AB-, AB+ A-, O-
B Negative B-, B+, AB-, AB+ B-, O-
AB Negative AB-, AB+ AB-, A-, B-, O-

Dear- Indian education system…

Dear Indian Education System… I have decided to take a huge step, But, before that, you guys need to know a lot of things about me. I used to score amazing till std 10th when I scored well, leave alone my parents,  all my friends, neighbors, shopkeepers…  Even the watchman of my building started to say ” You are going to take Science. You will be an engineer” no. Don’t get me wrong. I don’t dislike Science.  Science is beautiful science is the ultimate truth but when I came in Std 10th the half-interested teachers in my school and coaching institute didn’t teach Science at all!  All they taught was how to solve maximum number of MCQs in a given time, like a robot that killed the beauty of Science sir.  And that Physic’s topper of my class  He didn’t believe that evolution actually happened  He just wanted to solve maximum number of MCQs  So much obsession with Science.

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Photo by Pixabay on Pexels.com

India hasn’t won a single Nobel Prize in Science  Since Independence  Nobel Prizes are just “awards” , you’ll say  India produces the maximum number of engineers per year  Yet, India ranks 60th  in the Global Innovation Index that means no major innovation has happened since Independence, all we keep saying is “Aryabhatta invented Zero” to be honest, after 10th, I wanted to study Physics, Graphic Designing, Coding, History, Music and English Literature Why couldn’t the evaluation of my intelligence and calibers be on the basis of these subjects?  Why should’ve I wasted my time studying subjects I didn’t want to study?  So, I left the damn coaching institute, used to get out of my home during coaching hours and used to read novels in the park, see new places to be honest, I felt free It felt good not to be a zombie I learnt graphic designing on my own  I listened to some beautiful music by Mozart and Rahman  I read Poetry, I taught myself Python, and I read some amazing write-ups  on various topics of Physics  I am taking a huge step.  I am dropping out no not because Steve Jobs, Bill Gates and Mark Zuckerberg are drop-outs, not because being a “dropout” is cool, and neither it is because of the frustration of failing.

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Dear Indian Education System I am dropping out simply because you do not make any sense and now, you’ll ask me, who will give me a job?  Who will feed me?  I believe somewhere somebody is there who’ll see my skills. Will value my creativity.  Who will value my intelligence, not my CGPA Yes, I failed. but I know there is a lot to do, observe, and learn only my marksheet says that I can’t do anything but I know I will do something good.

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an amazing writeup by FMF.